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The concomitant usage of benzodiazepines and opioids boosts the hazard of respiratory depression thanks to actions at diverse receptor sites inside the CNS that Regulate respiration.
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Protracted withdrawal indications might previous weeks to much more than twelve months. Consequently, there may be issues in differentiating withdrawal indications from possible re-emergence or continuation of signs for which the benzodiazepine was being used.
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